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Understanding Your Risk for Ovarian Cancer

Anyone with ovaries can develop ovarian cancer. 

Prevention is not yet possible, but certain factors play a role in raising and lowering your risk.  

Factors That Raise Ovarian Cancer Risk

Age

  • Being 55 years or older 

    • Most ovarian cancer cases develop after menopause 

Gynecological 

  • First full-term pregnancy after age 35

  • No full-term pregnancies 

  • Late menopause

  • Early onset periods

  • Endometriosis

  • Infertility

Hormone therapy after menopause

  • Estrogen treatment without progesterone 

Genetics

  • A family history of ovarian, breast or colorectal cancer

  • Having a genetic mutation for ovarian, breast or colorectal cancer

    • BRCA1, BRCA 2 or Lynch syndrome

    • Up to 1 in 4 ovarian cancers are caused by genetic mutations

A previous breast cancer diagnosis

Obesity

Factors that might increase your risk — but more studies are needed

Research is still ongoing linking ovarian cancer risks to:

  • Talcum powder

  • Fertility treatments

Factors That Lower Your Ovarian Cancer Risk

Birth control 

  • Birth control pills

  • IUDs

  • Tubal ligation 

DYK? Few doctors still recommend tubal ligation. It’s now common to remove the fallopian tubes for permanent sterilization. 

Gynecological factors

  • Breastfeeding 

  • Pregnancy carried to full-term

    • Each pregnancy carried to full-term lowers your risk further

  • Early menopause (before age 45)

Surgery

  • Salpingectomy

    • Removal of fallopian tubes, often done during another surgery

  • Bilateral salpingo-oophorectomy 

    • Removal of both ovaries and fallopian tubes

  • Hysterectomy

    • Removal of uterus alone

DYK? Most cases of ovarian cancer start with precancerous cells in the fallopian tubes 

Removing the fallopian tubes is a low-risk surgery that could reduce your ovarian cancer risk by a lot.

 

This educational resource was created with support from Daiichi Sankyo and Merck.